| Description | Trans-Aconitic acid is normally present in normal human urine, and it has been suggested that is present in larger amounts with Reye's syndrome and organic aciduria. trans-Aconitic acid is a substrate of enzyme trans-aconitate 2-methyltransferase (EC 2.1.1.144). Trans-aconitate in the urine is a biomarker for the consumption of soy products.trans-Aconitic acid is an antimicrobial agent that blocks the transformation of Leishmania donovani amastigotes to prostigotes. |
| Target activity | ATP citrate synthase:>1 mM(Ki,rat) |
| molecular weight | 174.11 |
| Molecular formula | C6H6O6 |
| CAS | 4023-65-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 55 mg/mL (315.9 mM) |
| References | 1. Kar S , Kar K , Bhattacharya P K , et al. Experimental visceral leishmaniasis: role of trans-aconitic acid in combined chemotherapy.[J]. Antimicrobial Agents and Chemotherapy, 1993, 37(11):2459-2465. |