Description | AHR antagonist 2 is an antagonist of the aryl hydrocarbon receptor. The IC50s for human AHR and mouse AHR are 0.885 and 2.03 nM, respectively. |
molecular weight | 418.37 |
Molecular formula | C20H17F3N4O3 |
CAS | 2338747-54-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 225.0 mg/mL (537.8 mM), Sonication is recommended. |
References | 1. Julien LEFRANC, et al. 2-hetarylpyrimidine-4-carboxamides as aryl hydrocarbon receptor anatgonists. WO2019101641A1. |