| Description | TH-Z145 is a potent FPPS inhibitor for the study of myeloma and lung cancer. |
| In vivo | In a pathogenic influenza model, TH-Z145 (20 μg, i.p.) demonstrates strong prophylactic effects[1]. |
| molecular weight | 394.34 |
| Molecular formula | C16H28O7P2 |
| CAS | 2260887-57-6 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 80 mg/mL (202.87 mM), Sonication is recommended. |
| References | 1. Xia Y, et al. The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery. Cell. 2018 Nov 1;175(4):1059-1073.e21. |