| Description | STO-609 acetate is selective, cell-permeable inhibitor of Ca2+-calmodulin-dependent protein kinase kinase (Ki: 80/15 ng/ml, for CaM-KKα/KKβ); competes for the ATP-binding site. It displays > 80-fold selectivity over CaMK1/2/4, PKC, MLCK, PKA and p42 MAPK. |
| Target activity | CaM-KKα:80ng/ml(ki), CaM-KKβ:15 ng/ml(ki) |
| molecular weight | 374.35 |
| Molecular formula | C19H10N2O3·C2H4O2 |
| CAS | 1173022-21-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 10 mM, Sonication is recommended. |
| References | 1. Tokumitsu H, et al. J Biol Chem. 2002 May 3;277(18):15813-8. |