| Description | PSB-15160 is a compound that inhibits the growth of MCF7 (breast), NCI-H460 (lung) and SF-268 (NCS) cells in the treatment of estrogen-dependent tumours. |
| Target activity | GPR84:41.3 nM(EC50) |
| molecular weight | 282.29 |
| Molecular formula | C17H12F2N2 |
| CAS | 215997-93-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 60 mg/mL (212.55 mM) |
| References | 1. Pillaiyar T, et al. Diindolylmethane Derivatives: Potent Agonists of the Immunostimulatory Orphan G Protein-Coupled Receptor GPR84. J Med Chem. 2017 ; 60(9):3636-3655. |