| Description | PI3Kγ inhibitor 1 is a inhibitor of PI3Kδ and PI3Kγ. |
| In vitro | PI3Kγ inhibitor 1 ?inhibits PI3Kδ, PI3Kγ, PI3Kα and PI3Kβ with IC50s of <100 nM, <100 nM, <10 μM and <10 μM, respectively.?PI3Kγ inhibitor 1 inhibits B cell proliferation with an EC50<100 nM. |
| Target activity | PI3Kγ:100 nM, PI3Kα:10 μM, PI3Kβ:10 μM, PI3Kδ:100 nM |
| molecular weight | 586.67 |
| Molecular formula | C32H26N8O2S |
| CAS | 1172118-03-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Vito J. Palombella, et al. Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using pi3 kinase inhibitors. WO 2014004470 A1. |