| Description | PI3Kγ inhibitor 2 is an orally bioavailable inhibitor of PI3Kγ(Ki of 4 nM). |
| Target activity | PI3Kγ:4 nM (ki) |
| molecular weight | 433.38 |
| Molecular formula | C20H18F3N5O3 |
| CAS | 1315538-79-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Come JH, et al. Design and Synthesis of a Novel Series of Orally Bioavailable, CNS-Penetrant, Isoform Selective Phosphoinositide 3-Kinase γ (PI3Kγ) Inhibitors with Potential for the Treatment of Multiple Sclerosis (MS). J Med Chem. 2018 Jun 28;61(12):5245-5256. |