| Description | P110δ-IN-1 (PWT-143) is an effective and selective inhibitor of P110δ (IC50: 8.4 nM). |
| Target activity | p110δ:0.6 nM |
| Synonyms | PWT-143 |
| molecular weight | 604.77 |
| Molecular formula | C31H40N8O3S |
| CAS | 1595129-71-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 5 mg/mL (8.27 mM), Sonication is recommended. |
| References | 1. S. David Brown , et al. (sulfinyl and sulfonyl benzimidazolyl) pyrimidines and triazines, pharmaceutical compositions thereof, and their use for treating proliferative diseases. WO2014055647A1 |