| Description | Pancreatic Polypeptide, rat acetate is an agonist of NPY receptor, with high affinity at NPYR4. |
| In vitro | Pancreatic Polypeptide, rat acetate是NPY受体的激动剂，特别是在NPYR4上具有高亲和力。在BRIN BD11或1.1B4 β细胞中，1μM浓度的Pancreatic Polypeptide, rat acetate不会改变细胞增殖，但能逆转链脲佐菌素诱导的BRIN BD11细胞活力下降。0.1 nM至1μM浓度范围内，Pancreatic Polypeptide, rat acetate对分离的小鼠胰岛素分泌无影响，且在1μM浓度时不会改变BRIN BD11细胞的膜电位和(Ca2+)i水平[1]。 |
| In vivo | Pancreatic Polypeptide, rat acetate(25 nmol/kg bw, i.p.) 能降低葡萄糖刺激下的胰岛素浓度，但在经过一夜禁食的小鼠中对急性摄食行为没有影响[1]。 |
| molecular weight | N/A |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |