| Description | Oxelumab (R 4930) is a human monoclonal antibody for OX40L. Oxelumab could be used to study asthma. |
| In vitro | Oxelumab (10 μg/mL; 3天) 抑制NK细胞[2]的增殖。 |
| In vivo | Oxelumab（5及30 mg/kg；腹腔注射；每日一次；两剂）影响IL-6的浓度以及脾脏记忆T细胞和转换B细胞的频率[1]。 |
| Synonyms | Ro 49-89991, R 4930, huMAb OX 40L |
| molecular weight | N/A |
| CAS | 1186098-83-8 |
| Storage | store at low temperature | store at -80°C |
| References | 1. Youngblood BA, et al. AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice. Int Arch Allergy Immunol. 2019;180(2):91-102. 2. Kweon S, et al. Expansion of Human NK Cells Using K562 Cells Expressing OX40 Ligand and Short Exposure to IL-21. Front Immunol. 2019 Apr 24;10:879. |