| Description | ARS-1630 is a mutant K-ras G12C inhibitor. It is a less active enantiomer of ARS-1620. |
| molecular weight | 430.84 |
| Molecular formula | C21H17ClF2N4O2 |
| CAS | 1698055-86-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 100 mg/mL (232.10 mM) |
| References | 1. Liansheng Li, et al. Inhibitors of kras g12c. WO 2015054572 A1. 2. Janes MR, et al. Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor. Cell. 2018 Jan 25;172(3):578-589.e17. |