| Description | Nrf2 Activator-7 (Compound 12b) effectively enhances the Nrf2 signaling pathway as a potent Nrf2 activator. |
| In vitro | Nrf2激活剂-7与Keap1结合活性的IC50值经由荧光偏振（FP）测量为85 nM，利用时间分辨荧光能量转移（TR-FRET）测量为13.1 nM，Ki值报告为4.9 nM[1]。在给药浓度为1、10、100 μM，作用时间24小时后，Nrf2激活剂-7可显著提升Nrf2靶基因（GSTM3、HMOX1、NQO1）的转录水平[1]。 |
| molecular weight | 720.77 |
| Molecular formula | C35H32N2O11S2 |
| CAS | 2456295-39-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |