| Description | Keap1-Nrf2-IN-15 (Compound 24a) is a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, displaying IC50 values of 77 nM in a fluorescence polarization (FP) assay and 2.5 nM in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay [1]. |
| In vitro | Keap1-Nrf2-IN-15（化合物24a）能够与Keap1蛋白发生结合[1]。在浓度为10及100 μM、作用时间为24小时的条件下，Keap1-Nrf2-IN-15显著诱导NCM460D细胞内Nrf2靶基因（HMOX1、GSTM3、NQO1）的表达[1]。 |
| molecular weight | 801.84 |
| Molecular formula | C39H35N3O12S2 |
| CAS | 2456295-45-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |