Description | Nemolizumab (CIM331) is a humanized monoclonal antibody against human interleukin-31 receptor A that inhibits the binding and subsequent signal transduction of interleukin-31 (IL-31) to its receptor. Nemolizumab can be used to study atopic dermatitis with pruritus. |
Synonyms | CIM331 |
molecular weight | N/A |
CAS | 1476039-58-3 |
Storage | store at low temperature | store at -80°C |
References | 1. Nakahara T, et, al. Nemolizumab and Atopic Dermatitis: the Interaction Between Interleukin-31 and Interleukin-31 Receptor as a Potential Therapeutic Target for Pruritus in Patients With Atopic Dermatitis. 2018;5:405–14. |