| Description | L-006235 is a potent and reversible inhibitor of cathepsin K with IC50 of 0.25 nM. |
| Target activity | Cathepsin K:5 nM (IC50) |
| Synonyms | L 006235 |
| molecular weight | 466.6 |
| Molecular formula | C24H30N6O2S |
| CAS | 294623-49-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 50 mg/mL (107.16 mM) |
| References | 1. Lena Svelande , Helena Erlandsson-Harris, Leif Astner, et al.Inhibition of cathepsin K reduces bone erosion, cartilage degradation and inflammation evoked by collagen-induced arthritis in mice.Eur J Pharmacol. 2009 Jun 24;613(1-3):155-62. |