| Description | Isosorbide (Devicoran) is a heterocyclic compound that is derived from glucose, used as a diuretic. |
| In vitro | Isosorbide 通过增加尿液中渗透性活性溶质的量来增加尿量。渗透性利尿剂还能提高血浆的渗透压。Isosorbide 用于预防或治疗胸痛（心绞痛）。其机制是通过放松通往心脏的血管，从而增加了心脏的血液和氧气供应。[1] |
| Synonyms | Devicoran, Isobide, 异山梨酯, 异山梨醇, Hydronol, Dianhydro-D-glucitol, D-Isosorbide |
| molecular weight | 146.14 |
| Molecular formula | C6H10O4 |
| CAS | 652-67-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 50 mg/mL (342.14 mM) H2O: 100 mg/mL (684.28 mM) |
| References | 1. Lee, J., Kim, H., Jung, J., Kim, S., Kim, B., & Kim, K. (2016). Is dehydration test using isosorbide useful in Meniere’s disease?. Acta Oto-Laryngologica, 136(11), 1107-1109. doi: 10.1080/00016489.2016.195917 |