| Description | Cystamine dihydrochloride is a radiation-protective agent. It also protects against carbon tetrachloride liver damage. |
| molecular weight | 225.19 |
| Molecular formula | C4H14Cl2N2S2 |
| CAS | 56-17-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 55 mg/ml (244.24 mM) H2O: 50 mg/mL (222.03 mM), Sonication is recommended. |
| References | 1. Roncoroni L, Elli L, Braidotti P, et al. Transglutaminase 2 Mediates the Cytotoxicity of Resveratrol in a Human Cholangiocarcinoma and Gallbladder Cancer Cell Lines. Nutr Cancer. 2018 May 14:1-9. 2. Wang H, Liu WZ, Tang F, Sui HJ, Zhan XJ, Wang H. Cystamine slows but not inverses the progression of monocrotaline induced-pulmonary arterial hypertension in rats. Can J Physiol Pharmacol. 2018 Apr 10. doi: 10.1139/cjpp-2017-0720. [Epub ahead of print] PubMed PMID: 29633623. 3. Zhou Y, Hu Y, Sun W, Lu S, Cai C, Peng C, Yu J, Popovtzer R, Shen M, Shi X. Radiotherapy-Sensitized Tumor Photothermal Ablation Using γ-Polyglutamic Acid Nanogels Loaded with Polypyrrole. Biomacromolecules. 2018 Apr 6. doi: 10.1021/acs.biomac.8b00184. [Epub ahead of print] PubMed PMID: 29601720. 4. Fraser-Pitt DJ, Mercer DK, Smith D,et al. Cysteamine, an Endogenous Aminothiol, and Cystamine, the Disulfide Product of Oxidation, Increase Pseudomonas aeruginosa Sensitivity to Reactive Oxygen and Nitrogen Species and Potentiate Therapeutic Antibiotics against Bacterial Infection. Infect Immun. 2018 May 22;86(6). pii: e00947-17. |