| Description | IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM. |
| Target activity | cGAS:2.1 nM (IC50), IRAK4:2.8 nM (IC50) |
| molecular weight | 340.37 |
| Molecular formula | C22H16N2O2 |
| CAS | 1850276-58-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 24 mg/mL(70.51 mM) |
| References | 1. One class has the naphthalene second dione compounds and its derivative of protease modification activities. CN107163044A. |