| Description | PF-06928215 is an inhibitor of cGAS (cyclic GMP-AMP Synthase) (IC50 of 4.9 μΜ). |
| Target activity | cGAS:4.9 μM |
| molecular weight | 380.4 |
| Molecular formula | C20H20N4O4 |
| CAS | 2378173-15-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 33.33 mg/mL (87.62 mM), Sonication is recommended. |
| References | 1. Hall J, et al. Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay. PLoS One. 2017 Sep 21;12(9):e0184843. |