| Description | GSK-3β inhibitor 15 (Compound 54), with an IC50 of 3.4 nM, effectively suppresses Aβ 1-42-induced phosphorylation of GSK-3β and tau protein, as well as LPS-induced iNOS expression. It demonstrates neuroprotective properties against Aβ 1-42-induced neurotoxicity, indicating its potential utility in Alzheimer's disease (AD) research [1]. |
| molecular weight | 352.41 |
| Molecular formula | C17H16N6OS |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |