| Description | CTL-12, a fatty acid synthase (FASN) inhibitor (IC50: 2.5 μM), induces apoptosis and disrupts the cell cycle at the Sub-G1/S phase. It upregulates caspase-9 and the apoptosis marker Bax, while downregulating the anti-apoptotic marker Bcl-xL. By inhibiting de novo lipogenesis, CTL-12 thwarts tumor cells' metabolic requirements and is frequently employed in breast and colorectal cancer studies [1]. |
| molecular weight | 440.88 |
| Molecular formula | C22H21ClN4O4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |