| Description | GRGDSPC acetate (GRGDSPC acetate (91575-26-7 free base)) is a 7-amino acid peptide of thiolated cell adhesion. |
| In vitro | 通过硫醇-丙烯酸酯反应，将Thiolated cell adhesion peptides（GRGDSPC）与丙烯酸化的葡聚糖偶联，以调控人类间充质干细胞（hMSCs）与光交联水凝胶的相互作用。这些水凝胶能够在7周内持续释放短干扰RNA（siRNA），且与hMSCs具有良好的细胞相容性。从这些光交联的DEX水凝胶持续呈现出的siRNA增强了封装hMSCs的成骨分化。具有可调节的siRNA传递和细胞黏附特性的这些DEX水凝胶，可能为生物活性分子输送和组织再生应用提供一个优良平台。 |
| Synonyms | GRGDSPC, GRGDSPC acetate(91575-26-7 free base) |
| molecular weight | 750.78 |
| Molecular formula | C27H46N10O13S |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Nguyen MK, et al. Photocrosslinkable, biodegradable hydrogels with controlled cell adhesivity for prolonged siRNAdelivery to hMSCs to enhance their osteogenic differentiation. J Mater Chem B. 2017 Jan 21;5(3):485-495. |