| Description | Spongosine (2-Methoxy adenosine) is a pivotal intercellular signal transmitter, which has demonstrated a diverse bioactivity profile including anti-inflammatory activity and analgesic and vasodilation properties. Spongosine is a natural product isolated from Marine organisms, and first isolated from the marine sponge Cryptotethia crypta in 1950 |
| In vitro | Spongosine在3 μg/mL[1]的浓度下，展示了最强的抗炎效果，可使一氧化氮的产生量减少约60%。 |
| Synonyms | 2-Methoxy adenosine |
| molecular weight | 297.27 |
| Molecular formula | C11H15N5O5 |
| CAS | 24723-77-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 2.97 mg/mL (10 mM), Sonication is recommended. |
| References | 1. Bertin MJ, et al. Spongosine production by a Vibrio harveyi strain associated with the sponge Tectitethya crypta. J Nat Prod. 2015 Mar 27;78(3):493-9. 2. Huang, et al. Marine Nucleosides: Structure, Bioactivity, Synthesis and Biosynthesis. Mar. Drugs 2014, 12, 5817-5838. |