| Description | Gomisin M2 is an anti-HIV agent. |
| In vitro | Bioactivity-directed fractionation of an ethanolic extract of the fruits of Schisandra rubriflora led to the isolation and identification of dibenzocyclooctadiene lignans including the new lignans rubrisandrins A (1a + 1b) and B (2) and the known lignans gomisin J (3), (+/-)-gomisin M1 (4), (+)-Gomisin M2 (5), schisanhenol (6), deoxyschisandrin, schisantherin B, schisandrin, tigloylgomisin P, gomisin O, angeloylgomisin P, and epigomisin O. Their structure and stereochemistry were determined by spectroscopic methods, including 2D-NMR techniques. |
| Target activity | HIV:2.4 μM (EC50) |
| Synonyms | 五味子脂素 M2 |
| molecular weight | 386.444 |
| Molecular formula | C22H26O6 |
| CAS | 82425-45-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Rubrisandrins A and B, lignans and related anti-HIV compounds from Schisandra rubriflora.J Nat Prod. 2006 Dec;69(12):1697-701. |