| Description | 8-Prenylluteone can potently inhibit HIV-1 PR activity. |
| In vitro | The prenylated isoflavone structures, identified by spectroscopic analysis, were 8-Prenylluteone ( 1), auriculatin ( 2), erysenegalensein O ( 3), erysenegalensein D ( 4), erysenegalensein N ( 5), derrone ( 6), alpinumisoflavone ( 7), and 6,8-diprenylgenistein ( 8). The constituents showed dose-dependent inhibitory activities on HIV-1 PR with IC (50) values from 0.5 to 30.0 muM. |
| molecular weight | 422.47 |
| Molecular formula | C25H26O6 |
| CAS | 125002-91-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Prenylisoflavonoids from Erythrina senegalensis as novel HIV-1 protease inhibitors.Planta Med. 2009 Feb;75(3):268-70. |