Description | Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a proton pump inhibitor indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagitis.Esomeprazole magnesium trihydrate acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H+-ATPases |
Synonyms | 埃索美拉唑镁三水合物, 埃索美拉唑镁(三水), (S)-Omeprazole magnesium trihydrate |
molecular weight | 767.17 |
Molecular formula | C34H42MgN6O9S2 |
CAS | 217087-09-7 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 50 mg/mL (65.17 mM), Sonication is recommended. |
References | 1. Johnson TJ, Hedge DD. Esomeprazole: a clinical review. Am J Health Syst Pharm. 2002 Jul 15;59(14):1333-9. 2. Sandstr?M M , Davidson G , Tolia V , et al. Phase I, Multicenter, Randomized, Open-Label Study Evaluating the Pharmacokinetics and Safety Profile of Repeated Once-Daily Doses of Intravenous Esomeprazole in Children 0 to 17 Years of Age[J]. Clinical Therapeutics, 2012, 34(8):1828-1838. |