| Description | Elinafide, a dinaphthylimide cytotoxic agent, is a DNA-targeted anticancer agent that has shown antitumor activity in in vitro and in vivo assays. |
| Target activity | Smooth muscle cells (SMCs):12 nM, NCI-H460 cells:8 nM |
| molecular weight | 520.58 |
| Molecular formula | C31H28N4O4 |
| CAS | 162706-37-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: < 1 mg/mL (insoluble） |
| References | 1. Braña MF, et al. Naphthalimides as anti-cancer agents: synthesis and biological activity. Curr Med Chem Anticancer Agents. 2001;1(3):237-255. 2. Ferri N, et al. Synthesis, structural, and biological evaluation of bis-heteroarylmaleimides and bis-heterofused imides. Bioorg Med Chem. 2011;19(18):5291-5299. |