| Description | GSK329 is an effective and selective inhibitor of TNNI3 Interacting Kinase (TNNI3K). GSK329 exhibits positive cardioprotective outcomes in the model of ischemia/reperfusion cardiac injury. |
| Synonyms | GSK 329, GSK-329 |
| molecular weight | 472.25 |
| Molecular formula | C19H14Cl2F3N5O2 |
| CAS | 1268490-12-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 245 mg/mL (518.79 mM), Sonication is recommended. |
| References | 1. Patterson JR, et, al. Identification of Diarylurea Inhibitors of the Cardiac-Specific Kinase TNNI3K by Designing Selectivity Against VEGFR2, p38α, and B-Raf. J Med Chem. 2021 Nov 11;64(21):15651-15670. |