| Description | Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II. |
| In vivo | Compound CDy9 (100 μ M; 24-48 hours) exhibits no cytotoxicity to HEK-293 T cells, with cell viability>90% (versus control) [1]. |
| Target activity | CA II (human):0.18 μM |
| molecular weight | 336.36 |
| Molecular formula | C15H16N2O5S |
| CAS | 952306-80-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 27.5 mg/mL (81.76 mM) |
| References | 1. Zahid Hussain, et al. Synthesis and Evaluation of Amide and Thiourea Derivatives as Carbonic Anhydrase (CA) Inhibitors. ACS Omega. 2022 Dec 6;7(50):47251-47264. |