| Description | CIA-1 (Free base) is a nuclear receptor COUP-TFII inhibitor with IC50 values ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines. CIA-1 (Free base) inhibits tumor growth in a mouse model of prostate cancer xenografts. |
| Synonyms | CIA-1(Free base） |
| molecular weight | 329.42 |
| Molecular formula | C17H19N3O2S |
| CAS | 452087-38-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 60 mg/mL (182.14 mM) |
| References | 1. Renshaw RW, et al. A hypervariable region in VP1 of chicken infectious anemia virus mediates rate of spread and cell tropism in tissue culture. J Virol. 1996;70(12):8872-8878. 2. Hu LB, et al. Depletion of CD4+ and CD8+ T lymphocyte subpopulations by CIA-1, a chicken infectious anemia virus. Avian Dis. 1993;37(2):492-500. 3. Matsumoto T, et al. Characterization of CIA-1, an Ambler class A extended-spectrum β-lactamase from Chryseobacterium indologenes. Antimicrob Agents Chemother. 2012;56(1):588-590. |