Description | Carboxyamidotriazole is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways. It shows anti-inflammatory, anti-tumor, and antiangiogenic effects. |
Synonyms | CAI, L-651582 |
molecular weight | 424.67 |
Molecular formula | C17H12Cl3N5O2 |
CAS | 99519-84-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
References | 1. Chen C, et al. Carboxyamidotriazole Synergizes with Bay 43-9006 to Combat Non-Small Cell Lung Cancer through Inhibition of NANOG and Aggravation of Apoptosis. J Pharmacol Exp Ther. 2017 Aug;362(2):219-229. 2. Hussain MM, et al. J Clin Oncol. 2003 Dec 1;21(23):4356-63. |