| Description | Carbenicillin disodium (BRL-2064) is a broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. |
| In vitro | 在囊性纤维化患者中,Carbenicillin（0.1μg/ mL）未显示任何抗体水平的过敏性药物反应. 在菊花和TOBC中,arbenicillin (50 μg/mL) 能够以浓度依赖的方式导致植物毒性. |
| In vivo | Carbenicillin （125 mg / L）能够抑制土壤杆菌的增殖,增加体细胞胚胎的体积和和单个愈伤组织体细胞胚的数量。在愈合组织中,Carbenicillin (250 mg/L-500 mg/L)可增组织的鲜重增加。Carbenicillin (1 g/L) 降低叶盘外植体的发芽频率。在体外分离的患者的白细胞,经过 Carbenicillin（0.1 g/ml）作用,不会释放组胺。 |
| Synonyms | BRL-2064, 羧苄青霉素钠, Sodium carbenicillin |
| molecular weight | 422.36 |
| Molecular formula | C17H16N2Na2O6S |
| CAS | 4800-94-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | H2O: 77 mg/mL (182.3 mM) Ethanol: < 1 mg/mL (insoluble or slightly soluble) DMSO: 60 mg/mL (142.06 mM) |
| References | 1. TA Yu, et al. Bot. Bull. Acad. Sin, 2001, 42, 281-286. 2. Birgitte Nauerby, et al. Plant Science, 1997, 123 ,169- 177. 3. Sarma KS, et al. Journal of Experimental Botany, 1995, 46(11), 1779-1781. 4. Miller NE, et al. Allergy, 1980, 35(2), 135-138. 5. Teixeira da Silva JA, et al. J. Appl. Hort., 2001, 3(1), 3-12. |
| Citations | 1. Lim S Y M, Alshawsh M A, Alshagga M, et al.CYP Gene Expression and In Vivo Biological Effects of Khat Ethanol Extract, Cathinone and Cathine in Caenorhabditis elegans.Progress In Microbes & Molecular Biology.2023, 6(1). |