Description | Astegolimab (RG 6149) is a humanised IgG2 monoclonal antibody that targets the IL-33 receptor and inhibits IL-33 signalling. Astegolimab is used in the study of chronic obstructive pulmonary disease (COPD) and severe asthma in adults. |
Synonyms | RG 6149, MSTT 1041A |
molecular weight | N/A |
CAS | 2173054-79-8 |
Storage | store at low temperature | store at -80°C |
References | 1. Steven G Kelsen, et al. Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: A randomized clinical trial. J Allergy Clin Immunol. 2021 Sep;148(3):790-798. |