Description | Afamelanotide acetate is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist, used to for Erythropoietic Protoporphyria. |
Synonyms | afamelanotide |
molecular weight | 1706.9 |
Molecular formula | C80H115N21O21 |
CAS | 1566590-77-9 |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 22.5 mg/mL (13.18 mM) |
References | 1. Langendonk J G , Balwani M , Anderson K E , et al. Afamelanotide for Erythropoietic Protoporphyria[J]. New England Journal of Medicine, 2015, 373(1):48-59. 2. Kim E S , Garnock-Jones K P . Afamelanotide: A Review in Erythropoietic Protoporphyria[J]. American Journal of Clinical Dermatology, 2016, 17(2):179-185. |