| Description | PG 106 acetate is an effective and selective antagonist of the human melanocortin 3 (hMC3) receptor with an IC50 of 210 nM. PG 106 acetate has no activity with the hMC5 receptor and hMC4 receptors with an EC50 of 9900 nM. |
| Target activity | MC3R (human):210 nM |
| Synonyms | PG 106 acetate(944111-22-2 Free base) |
| molecular weight | 1068.23 |
| Molecular formula | C53H73N13O11 |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Paolo Grieco, et al. Further structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5. Peptides |