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1,7-Bis-Boc-1,4,7-triazaheptane

CAS No.: 117499-16-8

1,7-Bis-Boc-1,4,7-triazaheptane is an alkyl/ether-based PROTAC linker utilized for the synthesis of PROTACs[1].
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Description 1,7-Bis-Boc-1,4,7-triazaheptane is an alkyl/ether-based PROTAC linker utilized for the synthesis of PROTACs[1].
In vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
molecular weight 303.4
Molecular formula C14H29N3O4
CAS 117499-16-8
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
References 1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562