Description | Stearoylethanolamide(N-(2-Hydroxyethyl)octadecanamide) is a cannabinoid compound present in the brains of humans, rats, and mice with pro-apoptotic activity. |
In vitro | Present in human, rat, and mouse brain in amounts comparable to the endocannabinoid anandamide (arachidonoylethanolamide; AEA), stearoylethanolamide (SEA) is an endocannabinoid-like compound with pro-apoptotic activity. Its regulation by NO is reported to be in a manner opposite to that observed for AEA[1]. |
Synonyms | N-(2-Hydroxyethyl)octadecanamide |
molecular weight | 327.55 |
Molecular formula | C20H41NO2 |
CAS | 111-57-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 30 mg/mL (91.59 mM), Sonication is recommended. |
References | 1. Maccarrone M, et al. Binding, degradation and apoptotic activity of stearoylethanolamide in rat C6 glioma cells. Biochem J. 2002 Aug 15;366(Pt 1):137-44. |