| Description | Obtucarbamate A isolated from Disporum cantoniense has antitussive activity.It has antitussive activity, it exhibits significant inhibitory effect against neuroinflammation with the IC50 value of 10.57 μM . |
| In vitro | obtucarbamates A 对神经炎症表现出显著的抑制作用,其IC50值为10.57μM,远强于阳性对照物质minocycline的抑制效果(IC50值为35.82μM)。 |
| Synonyms | 4-甲基苯-1,3-二氨基甲酸二甲酯, 钝叶扁柏氨基甲酸酯 A, 钝叶扁柏氨基甲酸酯A |
| molecular weight | 238.24 |
| Molecular formula | C11H14N2O4 |
| CAS | 6935-99-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 2.38 mg/mL (10 mM) |
| References | 1. Biotransformation of isofraxetin-6-O-β-d-glucopyranoside by Angelica sinensis (Oliv.) Diels callus.Bioorg Med Chem Lett. 2017 Jan 15;27(2):248-253 |