| Description | Bruceoside A is a bitter wood glycoside that can be isolated from opuntia and has anticancer and tumor activity and can be used with the study of leukemia. |
| In vitro | 在体外实验中，与P-388细胞的氧化磷酸化作用的抑制效果相似，发现了brusatol、Bruceoside A和bruceantin[1]均表现出了类似的抑制效应。 |
| In vivo | Bruceoside A 在体内可以转化为具有强大抗癌活性的成分brusatol，而不是直接代谢成其脱糖形式bruceosin[2]。 |
| molecular weight | 682.67 |
| Molecular formula | C32H42O16 |
| CAS | 63306-30-9 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 100 mg/mL (146.48 mM), Sonication is recommended. |
| References | 1. Eigebaly SA, et al. Antitumor agents. XXXV: Effects of brusatol, bruceoside A, and bruceantin on P-388 lymphocytic leukemia cell respiration. J Pharm Sci. 1979 Jul;68(7):887-90. 2. Yuan Xu, et al. Pharmacokinetic study on bruceoside A revealed the potential role of quassinoid glycosides for the anticancer properties of Fructus Bruceae. J Pharm Biomed Anal. 2019 Jun 5;170:264-272. |