| Description | 1. Brazilin (Braziletto) exhibits anti-hepatotoxic, antiplatelet effects. 2. Brazilin has cancer preventive effect, may inhibit T24 cell growth and trigger cell death through a c-Fos-mediated and tumor cell specific signaling pathway. 3. Brazilin has anti-inflammatory property, can suppress mastitis and high glucose-induced vascular inflammatory process related with the inhibition of oxidative stress, CAMs expression, and NF-κB activation in HUVEC; may be useful to treat chronic inflammatory disorders including rheumatoid arthritis. |
| Synonyms | Natural Red 24, 巴西苏木素;苏枋精, Braziletto, Brasilin, Superbresiline, 巴西苏木素 |
| molecular weight | 286.28 |
| Molecular formula | C16H14O5 |
| CAS | 474-07-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 52 mg/mL(181.6 mM) Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble |
| References | 1. Lee Y R , Noh E M , Han J H , et al. Brazilin inhibits UVB-induced MMP-1/3 expressions and secretions by suppressing the NF-κB pathway in human dermal fibroblasts[J]. European Journal of Pharmacology, 2012, 674(2-3):80-86. |