| Description | α-Angelica lactone has cardiotonic activity, may exert their effects by providing an increased contraction-dependent calcium pool to be released upon systolic depolarization. |
| In vivo | α-angelicalactone, inhibited benzo(a)pyrene-induced neoplasia of the mouse forestomach and was more potent in this regard than coumarin. |
| Synonyms | α-当归内酯, 当归内酯, Alpha-Angelica Lactone |
| molecular weight | 98.1 |
| Molecular formula | C5H6O2 |
| CAS | 591-12-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 22.5 mg/mL (229.36 mM) |
| References | 1. Wattenberg L W , Lam L K , Fladmoe A V . Inhibition of chemical carcinogen-induced neoplasia by coumarins and alpha-angelicalactone.[J]. cancer research, 1979, 39(5):1651-1654. 2. Nijhoff W A , Bosboom M A , Smidt M H , et al. Enhancement of rat hepatic and gastrointestinal glutathione and glutathione S-transferases by α-angelicalactone and flavone[J]. Carcinogenesis, 1995, 16(3):607-612. |