| Bioactivity | ω-Conotoxin SO3 is a blocker of N-type voltage-sensitive calcium channel. ω-Conotoxin SO3 is an analgesicω-conotoxin that can be isolated from the venom of C. striatus[1][2]. |
| Name | ω-Conotoxin SO3 |
| CAS | 441284-32-8 |
| Sequence | Cys-Lys-Ala-Ala-Gly-Lys-Pro-Cys-Ser-Arg-Ile-Ala-Tyr-Asn-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Ser-Gly-Lys-Cys-NH2 (Disulfide bridge: Cys1-Cys16, Cys8-Cys20 and Cys15-Cys25) |
| Shortening | CKAAGKPCSRIAYNCCTGSCRSGKC-NH2 (Disulfide bridge: Cys1-Cys16, Cys8-Cys20 and Cys15-Cys25) |
| Formula | C100H166N36O31S6 |
| Molar Mass | 2561.00 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wen L, et al, a new O-superfamily conopeptide derived from Conus striatus, selectively inhibits N-type calcium currents in cultured hippocampal neurons. Br J Pharmacol. 2005 Jul;145(6):728-39. [2]. Yan LD, et al. Spinal antinociception of synthetic omega-conotoxin SO-3, a selective N-type neuronal voltage-sensitive calcium channel blocker, and its effects on morphine analgesia in chemical stimulus tests in rodent. Eur J Pharmacol. 2010 Jun 25;636(1-3):73-81. |
ω-Conotoxin SO3
CAS: 441284-32-8 F: C100H166N36O31S6 W: 2561.00
ω-Conotoxin SO3 is a blocker of N-type voltage-sensitive calcium channel. ω-Conotoxin SO3 is an analgesicω-conotoxin
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