Bioactivity | ω-Conotoxin CVIE is a voltage-gated Ca2+ channel (Ca v 2.2) selective inhibitor [1]. |
Name | ω-Conotoxin CVIE |
Sequence | Cys-Lys-Gly-Lys-Gly-Ala-Ser-Cys-Arg-Arg-Thr-Ser-Tyr-Asp-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Ser-Gly-Arg-Cys-NH2 (Disulfide bridge:Cys1-Cys16, Cys8-Cys20, Cys15-Cys25) |
Shortening | CKGKGASCRRTSYDCCTGSCRSGRC-NH2 (Disulfide bridge:Cys1-Cys16, Cys8-Cys20, Cys15-Cys25) |
Formula | C98H164N40O34S6 |
Molar Mass | 2638.99 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Berecki G, et al. Effects of arginine 10 to lysine substitution on ω-conotoxin CVIE and CVIF block of Cav2.2 channels. Br J Pharmacol. 2014 Jul;171(13):3313-27. |