ω-Conotoxin CVIB_product_DataBase

CAS: 325164-09-8 F: C102H173N41O32S7 W: 2710.18

ω-Conotoxin CVIB is a non-selective N- and P/Q-type voltage-gated calcium channels (VGCCs) antagonist. ω-Conotoxin CVI

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	ω-Conotoxin CVIB is a non-selective N- and P/Q-type voltage-gated calcium channels (VGCCs) antagonist. ω-Conotoxin CVIB inhibits depolarization-activated whole-cell VGCC currents in dorsal root ganglion (DRG) neurons with a pIC50 of 7.64[1].
Name	ω-Conotoxin CVIB
CAS	325164-09-8
Sequence	Cys-Lys-Gly-Lys-Gly-Ala-Ser-Cys-Arg-Lys-Thr-Met-Tyr-Asp-Cys-Cys-Arg-Gly-Ser-Cys-Arg-Ser-Gly-Arg-Cys-NH2 (Disulfide bridge:Cys1-Cys16, Cys8-Cys20, Cys15-Cys25)
Shortening	CKGKGASCRKTMYDCCRGSCRSGRC-NH2 (Disulfide bridge:Cys1-Cys16, Cys8-Cys20, Cys15-Cys25)
Formula	C102H173N41O32S7
Molar Mass	2710.18
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Leonid Motin, et al. Omega-conotoxin CVIB differentially inhibits native and recombinant N- and P/Q-type calcium channels. Eur J Neurosci. 2007 Jan;25(2):435-44.

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