| Bioactivity | σ1 Receptor antagonist-1 is a highly potent and selective sigma 1 receptor antagonist (pKi=10.28). σ1 Receptor antagonist-1 inhibits cell growth, arrests cell cycle at G0/G1 phase and induces apoptosis of MCF-7/ADR cells[1]. | ||||||||||||
| Invitro | σ1 Receptor antagonist-1 (compound 9) (10 μM; 48 hours) inhibits cell growth, arrests cell cycle at G0/G1 phase and induces apoptosis of MCF-7/ADR cells[1]. Cell Cycle Analysis[1] Cell Line: | ||||||||||||
| Name | σ1 Receptor antagonist-1 | ||||||||||||
| CAS | 1204401-49-9 | ||||||||||||
| Formula | C21H23NOS | ||||||||||||
| Molar Mass | 337.48 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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σ1 Receptor antagonist-1
CAS: 1204401-49-9 F: C21H23NOS W: 337.48
σ1 Receptor antagonist-1 is a highly potent and selective sigma 1 receptor antagonist (pKi=10.28). σ1 Receptor antagon
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