| Bioactivity | μ-Conotoxin SxIIIC is an irreversible NaV channel inhibitor that can be obtained from the Conus striolatus. μ-Conotoxin SxIIIC can be used in the study of neurological diseases such as chronic pain[1]. |
| Target | NaV channel. |
| Name | μ-Conotoxin SxIIIC |
| Sequence | Arg-Gly-Cys-Cys-Asn-Gly-Arg-Gly-Gly-Cys-Ser-Ser-Arg-Trp-Cys-Arg-Asp-His-Ala-Arg-Cys-Cys-NH2 (Disulfide bridge: Cys3-Cys15,Cys4-Cys21,Cys10-Cys22) |
| Shortening | RGCCNGRGGCSSRWCRDHARCC-NH2 (Disulfide bridge: Cys3-Cys15,Cys4-Cys21,Cys10-Cys22) |
| Formula | C90H142N42O27S6 |
| Molar Mass | 2436.75 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. McMahon KL, et al. Discovery, Pharmacological Characterisation and NMR Structure of the Novel µ-Conotoxin SxIIIC, a Potent and Irreversible NaV Channel Inhibitor. Biomedicines. 2020 Oct 2;8(10):391. |
μ-Conotoxin SxIIIC
CAS: F: C90H142N42O27S6 W: 2436.75
μ-Conotoxin SxIIIC is an irreversible NaV channel inhibitor that can be obtained from the Conus striolatus. μ-Conotoxi
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