| Bioactivity | δ-Sleep Inducing Peptide acetate is a neuropeptide, with antioxidant and anxiolytic properties[1][2]. | ||||||
| In Vivo | δ-Sleep Inducing Peptide (DSIP) 导致兔子体内纺锤体活动增加，心脏和呼吸频率适度降低[1]。δ-Sleep Inducing Peptide (DSIP; 40-360 μg/kg, 腹腔注射) 在 40 μg/kg 剂量下，增加大鼠体内过氧化氢酶和超氧化物歧化酶 (SOD) 活性以及急性应激大鼠肝脏匀浆中的丙二醛 (MDA) 浓度，但在 120 μg/kg 和 360 μg/kg 时观察到相反的效果[2]。 | ||||||
| Name | δ-Sleep Inducing Peptide acetate | ||||||
| Sequence | Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu | ||||||
| Shortening | WAGGDASGE | ||||||
| Formula | C37H52N10O17 | ||||||
| Molar Mass | 908.87 | ||||||
| Appearance | Solid | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
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| Reference | [1]. Monnier M, et al. The delta sleep inducing peptide (DSIP). Comparative properties of the original and synthetic nonapeptide. Experientia. 1977 Apr 15;33(4):548-52. [2]. Bobyntsev II, et al. Effect of Delta Sleep-Inducing Peptide on Functional State of Hepatocytes in Rats During Restraint Stress. Bull Exp Biol Med. 2016 Feb;160(4):421-4. |