| Bioactivity | δ-Cadinene ((+)-δ-Cadinene) is a sesquiterpene in essential oils. δ-Cadinene shows antiproliferative and pro-apoptotic effects on human ovary cancer (OVCAR-3) cells. δ-Cadinene has trichomonacidal, antimicrobial, antifungal and anticancer properties[1][2]. | ||||||
| Invitro | δ-Cadinene (0-100 µM；24-48 小时) 以浓度依赖性方式抑制 OVCAR-3 细胞的生长[2]。 δ-Cadinene (0-100 µM; 48 h) 以浓度依赖性方式诱导早期和晚期细胞凋亡[2]。 δ-Cadinene (0-100 µM; 48 h) 诱导 OVCAR-3 细胞中亚 G1 期生长停滞[2]。 OVCAR-3 cells0, 10, 50 and 100 µM 48 hInduced both early and late apoptosis.OVCAR-3 cells0, 10, 50 and 100 µM48 hLed to cell cycle arrest in sub-G1 phase. MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> δ-Cadinene 相关抗体: Cell Viability Assay[2] Cell Line: | ||||||
| CAS | 483-76-1 | ||||||
| Formula | C15H24 | ||||||
| Molar Mass | 204.35 | ||||||
| Appearance | 液体 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Store at room temperature 3 years
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| Reference | [1]. José Thyálisson da Costa Silva, et al. Eugenia Pohliana Leaves Essential Oil Inhibits Fungal Virulence and Restores Antibiotic Efficacy in Multidrug-Resistant Bacterial Strains. Chem Biodivers. 2024 Aug 15:e202401604. [2]. Li-Mei Hui, et al. δ-Cadinene inhibits the growth of ovarian cancer cells via caspase-dependent apoptosis and cell cycle arrest. Int J Clin Exp Pathol. 2015 Jun 1;8(6):6046-56. |