| Bioactivity | γ-Terpinene-d3 is deuterated labeled Cinnamyl Alcohol (HY-Y0078). Cinnamyl Alcohol is an active component from chestnut flower, inhibits increased PPARγ expression, with anti-obesity activity[1]. |
| Invitro | 氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> γ-Terpinene-d3 相关抗体: |
| In Vivo | γ-Terpinene (γ-TPN; 12.5, 25?mg/kg; p.o.; single dose) significantly reduces the licking time of the stimulated paw in both phases of the test in male Swiss mice (20-30?g)[2]. γ-Terpinene given either systemically (p.o.; 1.56, 3.125, and 6.25?mg/kg) or centrally (i.t or i.c.v; 10 and 20?μg/site) causes significant inhibition of glutamate-induced nociception in mice[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| Formula | C10H13D3 |
| Molar Mass | 139.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Flávia Franceli de Brito Passos, et al. Involvement of Cholinergic and Opioid System in γ-Terpinene-Mediated Antinociception. Evid Based Complement Alternat Med. 2015;2015:829414. [3]. Guo-Xiang Li, et al. Unusual antioxidant behavior of alpha- and gamma-terpinene in protecting methyl linoleate, DNA, and erythrocyte. J Agric Food Chem. 2009 May 13;57(9):3943-8. |