| Bioactivity | γ-L-Glutamyl-L-alanine, composed of gamma-glutamate and alanine, is a proteolytic breakdown product of larger proteins. γ-L-Glutamyl-L-alanine is a natural substrate of the γ-Glutamylcyclotransferase. γ-L-Glutamyl-L-alanine is a positive modulator of calcium-sensing receptor (CaR) function[1][2][3][4]. | ||||||||||||
| Invitro | γ-L-Glutamyl-L-alanine (γ-Glu-Ala) shows the potency for Ca2+i mobilization in CaR (calcium-sensing receptor)-expressing HEK-293 cells, with an EC50 of 4.8 µM[3].γ-L-Glutamyl-L-alanine shows the potency for Ca2+i mobilization in human parathyroid cells with an EC50 of 13.9 µM[3].γ-L-Glutamyl-L-alanine (20 μM) suppress PTH secretion from normal human parathyroid cells[3].γ-L-Glutamyl-L-alanine is a substrate for glutaminase B[4]. | ||||||||||||
| Name | γ-L-Glutamyl-L-alanine | ||||||||||||
| CAS | 5875-41-2 | ||||||||||||
| Formula | C8H14N2O5 | ||||||||||||
| Molar Mass | 218.21 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|
γ-L-Glutamyl-L-alanine
CAS: 5875-41-2 F: C8H14N2O5 W: 218.21
γ-L-Glutamyl-L-alanine, composed of gamma-glutamate and alanine, is a proteolytic breakdown product of larger proteins.
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.